One-year strabismus outcomes in the Infant Aphakia Treatment Study.

نویسندگان

  • Erick D Bothun
  • Julia Cleveland
  • Michael J Lynn
  • Stephen P Christiansen
  • Deborah K Vanderveen
  • Dan E Neely
  • Stacey J Kruger
  • Scott R Lambert
چکیده

OBJECTIVE To evaluate the characteristics of strabismus in infants who underwent cataract surgery with and without intraocular lens (IOL) implantation. DESIGN Secondary outcome analysis in a prospective, randomized clinical trial. PARTICIPANTS The Infant Aphakia Treatment Study is a randomized, multicenter (n = 12), clinical trial comparing treatment of aphakia with a primary IOL or contact lens in 114 infants with a unilateral congenital cataract. INTERVENTION Infants underwent cataract surgery with or without placement of an IOL. MAIN OUTCOME MEASURES The proportion of patients in whom strabismus developed during the first 12 months of follow-up was calculated using the life-table method and was compared across treatment groups and age strata using a log-rank test. RESULTS Strabismus developed within the first 12 months of follow-up in 38 pseudophakic infants (life-table estimate, 66.7%) and 42 infants (life-table estimate, 74.5%) treated with contact lenses (P = 0.59). The younger cohort (<49 days) at the time of surgery demonstrated less strabismus (29 of 50; life-table estimate, 58.0%) than the older cohort (≥ 49 days; 51 of 64; life-table estimate, 80.0%; P<0.01). CONCLUSIONS Intraocular lens placement does not prevent the early development of strabismus after congenital cataract surgery. However, strabismus was less likely to develop in infants whose cataract was removed at an earlier age. FINANCIAL DISCLOSURE(S) The author(s) have no proprietary or commercial interest in any materials discussed in this article.

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منابع مشابه

Sensorimotor outcomes by age 5 years after monocular cataract surgery in the Infant Aphakia Treatment Study (IATS).

PURPOSE To evaluate sensorimotor outcomes among children in the Infant Aphakia Treatment Study (IATS). METHODS Secondary outcome analysis was performed in this randomized, multicenter, clinical trial comparing treatment of unilateral aphakia with a primary intraocular lens (IOL) or contact lens (CL) correction. The alignment characteristics and sensory status of children through age 5 years w...

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عنوان ژورنال:
  • Ophthalmology

دوره 120 6  شماره 

صفحات  -

تاریخ انتشار 2013